![]() Fortunately, N-acetylcysteine (NAC) is a safe and effective antidote which if used correctly prevents serious hepatic injury after paracetamol overdose. While paracetamol is safe in normal doses, it is hepatotoxic and potentially fatal in overdose. ![]() ![]() It is also common to see accidental paediatric ingestion, unintentional self-administered supratherapeutic ingestions or intentional self-poisoning in the Emergency Department. Paracetamol is widely used for its analgesic/anti-pyretic effects.
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